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Patient story

"I’ve had amazing feedback from a patient who I gave a sample, she’s since purchased some more and has been telling people about them. She reported feeling calmer about food mentally and found she started choosing food she needed rather than wanted even on the first day of taking them."

Constance Armstrong CAVN #700361

Constance Armstrong CAVN #700361

Director of Nursing Operations

Prescription

Calocurb

4.5

100,000+ Happy Customers

As low as
$89.99 $79.99
or $2.58 per day
Feel Full Faster. Calocurb is the only clinically shown natural GLP-1 activator that stimulates your body’s internal signal to help you feel satisfied
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  • Reduces hunger by 30%

  • Cuts cravings by 40%

  • Supports natural weight loss

  • 100% plant-based ingredients

  • Clinically proven appetite control

  • Science-led, patented natural product

  • Trusted by doctors and scientists

  • Backed by independent published research

  • Vegetarian and 100% natural

  • Grown in New Zealand, made in the USA

  • More cost-effective than alternatives

A world leader in healthcare, Lonza® is the team behind our clever capsule. With more than eight years of research behind the patented design, it releases at the right spot in the digestive system to make Calocurb the most effective.

Benefits

You will feel full faster, have more control over portions and snacking, and manage your appetite more effectively"

30%

Reduction in hunger in an hour

40%

Reduction in cravings in an hour

18%

Reduction in calories consumed after an hour

Benefits
Features

Features

Fewer side effects than alternatives

Calocurb has shown a low incidence of side effects in studies. The desired effects of Calocurb are typically observed within an hour of consumption. It can reduce the feelings of hunger and cravings with clinical efficacy for up to 4 hours.

Tailored dosages for individualized care

We acknowledge that every person’s physiology is slightly different. Our 125mg capsules allow people to customize their dosage to best fit their body’s needs and gastric emptying rate.

Reconnecting the endogenous response

Calocurb stimulates the release of satiety hormones (CCK, GLP-1, and PYY) by up to 6 times baseline levels due to our capsule’s unique characteristics. These hormones then communicate with the appetite-suppression pathway in the brain, reducing feelings of appetite, cravings, and caloric intake.

Frequently asked

Frequently Asked Questions

Frequently Asked Questions about Calocurb: Your Affordable, Prescription-Free Solution

Amarasate® comes from a specific variety of Hops grown in New Zealand and has been clinically proven to reduce hunger by 30%, reduce cravings by 40% and reduce calorie intake by 18%, within an hour.

In clinical studies, Calocurb showed a low incidence of side effects when starting on Calocurb, and no ongoing side effects . Mild patient discomfort (e.g., loose stools) can occur in the first 24–72 hours as your body adjusts to the levels of GLP-1 you are now naturally activating. Gradually increasing your dose over a number of days helps minimize any discomfort.

  • Day 1 - 2: Take one capsule one hour before a meal.

  • Day 3 - 4: Take one capsule twice daily, one hour before meals.

  • Day 5+: Take two capsules twice daily, one hour before meals.

Max: Four capsules daily.

Best results when taken on an empty stomach, one hour before meals. The effects of Calocurb can last up to six hours after taking a capsule.

You can tailor your dosage daily, to take between 1-4 capsules.

Calocurb's active ingredient is Amarasate®, an extract from hops only grown in the South Island of New Zealand.

Amarasate® works by stimulating the gastric tastebuds to release a natural blend of gastric peptides GLP-1, CCK, and PYY. This triggers the 'bitter break' that helps the body effectively manage appetite, overeating, cravings, and hunger. In a GMP (Good Manufacturing Practice) credited facility, Amarasate® is gently blended with Calocurb's other two ingredients, rosemary leaf extract (a natural preservative) and a Non-GMO, glycophosphate-free canola oil (a stable, consistent oil that allows Amarasate® to disperse effectively upon contact with the gut surface).

The effects of Calocurb are typically felt within an hour. Most users feel Calocurb’s effects for several hours, helping them manage snacking and portion sizes.

No prescription is required. Calocurb is available online for anyone looking to support healthy eating habits.

Each bottle contains 90 capsules, typically a month’s supply at up to four capsules per day. Many users adjust their daily intake (1–4 capsules) to suit their needs.

By law, the FDA does not approve dietary supplements. But, the FDA does regulate both dietary supplements and dietary ingredients. Calocurb follows "current Good Manufacturing Practice" (cGMP) regulations requiring that manufacturers evaluate their products through testing identity, purity, strength, and composition.

Everyone has a different physiological makeup, so some people will experience the biological affect of Amarasate® differently. If you are one of the few who have started taking Calocurb and are not seeing any difference in appetite simply try increasing your capsules by 1x daily. If this is not working for you after a couple of days please get in touch with us to speak to a Direct Meds team member, sometimes all it takes is some experimenting to get into the right rhythm of when best to take your Calocurb.

Important

Calocurb is a natural supplement intended to support satiety and portion control. This product is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any new supplement. Not recommended for individuals under 18, or for those who are pregnant or breastfeeding. Results may vary.

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Safety info: GLP-1–based medications are used as part of medical weight-management programs for adults who meet specific clinical criteria. These medications may cause side effects, some of which can be serious (such as the potential risk of thyroid C-cell tumors). Do not use GLP-1 medications if you or your family have a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Always consult a healthcare professional before starting or changing any medication.

Medication (when prescribed) is included in the cost of the Direct Meds program. Medical treatment is provided and supervised by licensed healthcare professionals.

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