How Online Weight Loss Prescription Works

Every body is different, but most of our patients report reduced cravings and more control over food within the first 2–4 weeks. Visible weight loss often begins by week 6, with major progress seen over the first 3 to 6 months. Our licensed nurses check in throughout your journey to optimize dosing and support consistency.

Semaglutide and tirzepatide are both GLP-1–based medications used in medical weight-management programs, but they work through slightly different hormone pathways. Semaglutide acts on the GLP-1 receptor, which plays a role in appetite regulation, digestion, and blood-sugar control. Tirzepatide acts on the GLP-1 receptor as well, but also engages an additional hormone pathway known as GIP.
Your licensed provider will review your health history, goals, and preferences to help determine which option—if either—is appropriate for your individual needs. Treatment experiences vary from person to person, and your provider will guide you toward the approach that best fits your medical profile and comfort level.

Nope—no appointments needed. Everything is handled through a secure online quiz and virtual intake form that you can complete in minutes, from anywhere. Once submitted, a licensed medical provider reviews your case within just a few business hours. If you're approved, your personalized prescription is prepared and shipped directly to your door within 1 business day—no pharmacy lines or delays. Every patient also receives ongoing access to our nursing staff for questions, support, and follow-ups throughout the journey. It’s real medical care, made simple, and designed to fit your life—not the other way around.

Like any medication, GLP-1s can cause side effects, but most are mild and temporary. The most common include nausea, constipation, fatigue, or slight appetite changes in the first couple of weeks. These symptoms often subside as your body adjusts. That’s why we include nurse access with every plan—you’re never left guessing. If you ever feel unsure or need a dose adjustment, our team is here for you.

Injectable GLP-1 medications are typically taken once a week and are administered with a small subcutaneous injection. Some people prefer this format because it fits easily into a weekly routine.

Sublingual drops are placed under the tongue and are usually taken more frequently, depending on the provider’s instructions. This approach may appeal to individuals who prefer a needle-free option or who find daily dosing easier to remember.

Each option has different administration schedules and practical considerations, and experiences can vary. During your consultation, a licensed provider will review your medical history, discuss your preferences, and determine which format is appropriate for your individual care plan.

Yes—we are a fully LegitScript-certified, HIPAA-compliant telehealth provider with more than 53,000 satisfied patients and an average 4.8-star rating. We work exclusively with licensed providers and fully licensed pharmacies, and all prescriptions are reviewed by a real provider before being shipped. Our medications undergo third-party testing for purity, safety, and potency, and our entire patient experience is designed to be transparent, supportive, and results-driven. You won’t find hidden fees, questionable sourcing, or automated bots here—just high-quality care from real humans who care.

No hidden fees—ever. Our pricing is all-inclusive, meaning everything from the medication itself to nurse support, shipping, and digital follow-ups is bundled into one clear monthly rate. Plans start at $249/month for sublingual Semaglutide, and $297/month for injections. We also offer new customer discounts, bulk pricing for 6- or 12-month plans, and accept HSA/FSA payments. What you see is what you pay—no subscriptions, no surprise charges, and no pressure.

Absolutely. Direct Meds accepts HSA (Health Savings Account) and FSA (Flexible Spending Account) payments for all GLP-1 treatments. It’s a convenient way to use pre-tax dollars for medically necessary care. Once approved, we can provide receipts and documentation for reimbursement, if needed. This helps many of our patients make their care more affordable while staying compliant with insurance or employer guidelines.

Once you complete the intake quiz, your responses are securely reviewed by one of our licensed medical providers. If you qualify, your prescription is compounded at a certified U.S. pharmacy and shipped within 1 business day. You’ll receive tracking details by email or SMS, and from there, your journey begins. What makes Direct Meds different is the ongoing support—you’ll receive check-ins, nurse access, and a dedicated care team that helps track your progress, optimize your treatment, and make sure your experience is as effective and seamless as possible.

It’s very common for people to feel discouraged after trying multiple diets, workout routines, or supplements without seeing meaningful progress. Weight management is influenced by many biological factors—not just willpower—which is why some individuals explore medical options with their healthcare provider.

GLP-1–based medications are used in medical weight-management programs to influence hormone pathways related to appetite, digestion, and blood-sugar regulation. For some people, this approach—combined with nutritional guidance, lifestyle changes, and clinical oversight—may help support more consistent progress.

If you feel stuck, a licensed provider can review your history, discuss your goals, and determine whether a GLP-1–based treatment plan, including compounded options when appropriate, is suitable for you. Our team offers ongoing support, clear guidance, and an easy-to-follow virtual process to help you stay informed and supported throughout your journey.