How Online Weight Loss Prescription Works

Every body is different, but most of our patients report reduced cravings and more control over food within the first 2–4 weeks. Visible weight loss often begins by week 6, with major progress seen over the first 3 to 6 months. Our licensed nurses check in throughout your journey to optimize dosing and support consistency. Because our GLP-1 medications are clinically backed, the results are sustainable—not just fast, but lasting.

Great question. Both medications are powerful GLP-1 treatments, but Tirzepatide also activates a second hormone receptor called GIP, which may result in even greater weight loss for some people. On average, Tirzepatide patients lose around 21% of their body weight, compared to 15–16% with Semaglutide. That said, individual experiences vary. Our team helps you decide which medication is best based on your body, goals, and preferences—including the choice between injections or sublingual delivery.

Nope—no appointments needed. Everything is handled through a secure online quiz and virtual intake form that you can complete in minutes, from anywhere. Once submitted, a licensed medical provider reviews your case within just a few business hours. If you're approved, your personalized prescription is prepared and shipped directly to your door within 1 business day—no pharmacy lines or delays. Every patient also receives ongoing access to our nursing staff for questions, support, and follow-ups throughout the journey. It’s real medical care, made simple, and designed to fit your life—not the other way around.

Like any medication, GLP-1s can cause side effects, but most are mild and temporary. The most common include nausea, constipation, fatigue, or slight appetite changes in the first couple of weeks. These symptoms often subside as your body adjusts. That’s why we include nurse access with every plan—you’re never left guessing. If you ever feel unsure or need a dose adjustment, our team is here for you.

Our patients love having options. The injectable form is taken once a week with a small, painless shot—very easy and quick. The sublingual drops are taken under the tongue every 1–2 days and are perfect for those who prefer a needle-free option. Both forms use the same active ingredients and have similar outcomes. It really comes down to what fits your lifestyle better—and we help guide that choice during the intake process.

Yes—we are a fully LegitScript-certified, HIPAA-compliant telehealth provider with more than 53,000 satisfied patients and an average 4.8-star rating. We work exclusively with licensed providers and fully licensed pharmacies, and all prescriptions are reviewed by a real provider before being shipped. Our medications undergo third-party testing for purity, safety, and potency, and our entire patient experience is designed to be transparent, supportive, and results-driven. You won’t find hidden fees, questionable sourcing, or automated bots here—just high-quality care from real humans who care.

No hidden fees—ever. Our pricing is all-inclusive, meaning everything from the medication itself to nurse support, shipping, and digital follow-ups is bundled into one clear monthly rate. Plans start at $249/month for sublingual Semaglutide, and $297/month for injections. We also offer new customer discounts, bulk pricing for 6- or 12-month plans, and accept HSA/FSA payments. What you see is what you pay—no subscriptions, no surprise charges, and no pressure.

Absolutely. Direct Meds accepts HSA (Health Savings Account) and FSA (Flexible Spending Account) payments for all GLP-1 treatments. It’s a convenient way to use pre-tax dollars for medically necessary care. Once approved, we can provide receipts and documentation for reimbursement, if needed. This helps many of our patients make their care more affordable while staying compliant with insurance or employer guidelines.

Once you complete the intake quiz, your responses are securely reviewed by one of our licensed medical providers. If you qualify, your prescription is compounded at a certified U.S. pharmacy and shipped within 1 business day. You’ll receive tracking details by email or SMS, and from there, your journey begins. What makes Direct Meds different is the ongoing support—you’ll receive check-ins, nurse access, and a dedicated care team that helps track your progress, optimize your treatment, and make sure your experience is as effective and seamless as possible.

You’re not alone—many of our patients come to us after years of trying every diet, workout plan, and supplement with little to no success. The truth is, weight loss isn’t just about willpower—it’s biology. That’s where GLP-1 medications like Semaglutide and Tirzepatide can help. These treatments regulate appetite, slow digestion, and improve metabolic function, making it easier to lose weight and keep it off. If you’re feeling stuck, we offer a proven, medically supervised path forward—with personalized care, fast delivery, and real human support. This might finally be the solution that works for you.