Direct Meds

What do you need help with?

Take our quiz to find out if you qualify.

Not sure of what you need?
Clinically Backed Treatments
Clinically Backed Treatments
Doctor-Prescribed & Supervised
Doctor-Prescribed & Supervised
Convenient At-Home Delivery
Convenient At-Home Delivery
Personalized Care Plans
Personalized Care Plans
Transparent, All-Inclusive Pricing
Transparent, All-Inclusive Pricing
Clinically Backed Treatments
Clinically Backed Treatments
Doctor-Prescribed & Supervised
Doctor-Prescribed & Supervised
Convenient At-Home Delivery
Convenient At-Home Delivery
Personalized Care Plans
Personalized Care Plans
Transparent, All-Inclusive Pricing
Transparent, All-Inclusive Pricing

What do you need help with?

Discover the right solution for your goals. Whether you’re looking to shed extra pounds, regain energy, or simply feel better in your own skin—our expert team and proven medications can help you get there.

Not sure of what you need?

Lose Weight. Gain Confidence.
Live Better.
Look Younger. Feel Energized.
Live Vibrantly.
Regrow Hair. Restore Confidence.
Love Your Look.
Ease Pain. Move Freely.
Live Fully.
Build Muscle. Boost Strength.
Elevate Your Life.
Smooth Skin. Bright Glow.
Renew Confidence.

No memberships. No hidden fees. Just fast, medically guided results.
Take our quiz to find out if you qualify.
semaglutide (1)
NAD+
capilyn (1)
ortharex
sermorix (1)
elastira

What do you need help with?

Direct Meds is Better at Health

Trusted by over 53,000+ happy customersTrust Pilot

This month’s most popular medications

Popular medications

Back

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Tirzepatide Sublingual Liquid

Tirzepatide

$349.00 / mo.
Tirzepatide Medicine

Tirzepatide

$547.00 / mo.
Semaglutide Sublingual Liquid

Semaglutide

$299.00 / mo.
Semaglutide Medications

Semaglutide

$347.00 / mo.
Minoxalune Medicine

Minoxalune (Minoxidil)

$89.00 / mo.
Capilyn with Finasteride Medicine

Capilyn (Finesteride)

$89.00 / mo.
Elastira Medicine

Elastira

$139.00 / mo.
Ortharex Medicine

Ortharex

$139.99 / mo.
Revionyx Medicine

Revionyx (Epithalon)

$299.99 / mo.
Sermorix Medicine

Sermorix (Sermorelin)

$299.99 / mo.
Citradine Medicine

Citradine (Sinetrol)

$59.99 / mo.
SatiaLean

SatiaLean (DNF-10)

$59.99 / mo.
Anti-Aging Anti-Aging Anti-Aging
Hair Regrowth Hair Regrowth Hair Regrowth
Muscle Recovery Muscle Recovery Muscle Recovery
Pain Relief Pain Relief Pain Relief
Skin Skin Skin
Weight Loss Weight Loss Weight Loss
Not sure which is the right one for you?

Hundreds of people have changed their life with us.

Meet some of them

Carly B
5 stars

Carly B

"I am 50 years old and I have been on GLP-1 Medicine since October and I have lost 35 pounds. I have struggled with this 35 pound for the last 4 years.. and this medication just helps quiet the hunger in my head. I don’t feel hungry. I don’t have cravings. It's helped me get back to a clean diet…. It has helped me tremendously. Hopefully I can continue this journey and keep the weight off and have a great life."
Carly B
Carly B
Lucille W
5 stars

Lucille W

"My journey started really in October and I was 230 pounds. I now weigh 178 pounds with direct meds. I just love ‘em. After about 2 weeks all the side effects went away… And I got going again. I’m just not hungry anymore. They’re wonderful. "
Lucille W
Lucille W
Daryl
5 stars

Daryl H

"I’ve been on it for… 90 days….. and I have lost 45 pounds. My clothes are getting really big. I can tell it in my face, it’s tremendous. And I just thank you for the product. It is truly a miracle. And I want to thank all of my support people.… My blood sugar has gone down. My blood pressure is very normal, I have more energy. And I wanted to say to all of you… thank you. Thank you. And I hope I make good progress."
Daryl H
Daryl H
Crystal
5 stars

Crystal

"It definitely curbs your appetite and makes it easier not to eat!"
Crystal
Crystal
DavidWain
5 stars

David W

"I am 30 days in. I'm down 14 pounds. And I look forward to the next 14. Best thing that's ever happened."
David W
David W
Wendy
5 stars

Wendy A

"It makes me feel happy. It makes me feel more energetic. Makes me have more energy. And I love it. I’ve got about 10 more pounds that I want to get off…. I think I can stand a few more weeks of this. I like it. It really gives me that boost of energy that I need and curbs my cravings."
Wendy A
Wendy A

Ready to Start?

Discover the treatment that fits your body, your goals, and your lifestyle — all from home.

Semaglutide weight loss with ongoing nurse support

Real Care, From Real Nurses.

Our licensed nursing team is here for you from day one — with expert guidance, real answers, and personalized care.

The Problem

Most online providers leave patients on their own after checkout. No clear instructions, no real-time answers, and no one to turn to when questions come up.

What We Did

We built a nationwide network of licensed nurses who stay connected with patients from onboarding through ongoing treatment. Whether it’s side effects, dose adjustments, or just checking in — you’re never alone.

How it Went

Patients consistently rank our nursing support as one of the top reasons they chose Direct Meds — and why they stay. Confidence is higher. Confusion is lower. And treatment success rates. are stronger when support is built in.

home product slide glp 1

GLP-1 Typical Outcomes

Clinically-backed results you can trust—supported by real data and patient experiences.

0%

Report Better Appetite Control

0%

See improved metabolic & cardiovascular health

0%

Enjoy a higher quality of life

home product slide nad

NAD+ Typical Outcomes

Clinically-backed results you can trust—supported by real data and patient experiences.

50%

NAD+ levels decline by up to 50% between the ages of 40 and 60

21%

increase in muscle endurance and mitochondrial density in humans

93%

of participants reported reduced fatigue after 4 weeks of NAD+ IV therapy

home product slide calocurb

Calocurb Typical Outcomes

Clinically-backed results you can trust—supported by real data and patient experiences.

30%

Hunger reduction reported

40%

Craving reduction reported

14.3%

Reduction in rebound eating behaviors

home product slide sermorix

Sermorelin Typical Outcomes

Clinically-backed results you can trust—supported by real data and patient experiences.

37 mg/dL

Reduction in Triglycerides

13%

Fat Mass Decrease

10-15%

Lean Mass Increase ~10–15%

home product slide citradine

Sinetrol Typical Outcomes

Clinically-backed results you can trust—supported by real data and patient experiences.

15.6%

Body Fat in 12 Weeks

5.7%

Waist Circumference

4.7%

Hip Size Reduction

home product slide satialean

dNF-10 Typical Outcomes

Clinically-backed results you can trust—supported by real data and patient experiences.

100%

Weight loss observed during trials consisted of 100% fat mass, with no lean muscle lost.

5%

Subjects experienced an average 5% reduction in waist size—about 5 cm lost—after 10 weeks of DNF‑10 at 1 g/day.

6%

After just 4 weeks, users saw a 6% reduction in fat mass ratio using 500 mg/day.

online weight loss injections

Epithalon Typical Outcomes

Clinically-backed results you can trust—supported by real data and patient experiences.

Immune Function

Improved in Elderly Adults

Melatonin Secretion

Restored in Elderly Humans

Telomere
Length

Increased in Elderly Subjects

home product slide ortharex

Diclofenac Typical Outcomes

Clinically-backed results you can trust—supported by real data and patient experiences.

43%

Pain Reduction (Knee Osteoarthritis, 4 Weeks)

50%

Pain reduction with topical diclofenac in chronic pain

40%

Reduction in movement-related pain in 44% of users

home product slide elastira

Elastira Typical Outcomes

Clinically-backed results you can trust—supported by real data and patient experiences.

4-5%

Niacinamide 4-5% cream visibly reduces wrinkles, red blotches, and pore size in 8-12 weeks

5-20%

Glycolic Acid cream (5-20%) improve texture, tone, and collagen production in 3 months

collagen

Clinically proven to boost collagen and thicken skin: Tretinoin reduces fine lines & pigmentation

home product slide capilyn

Finesteride Typical Outcomes

Clinically-backed results you can trust—supported by real data and patient experiences.

66%

48% of Men Show Visible Improvement at 1 Year; 66% at 2 Years

83%

83% Showed No Further Hair Loss at 2 Years

21.6%

21.6% Hair Weight & +7.2% Hair Count Over 4 Years

home product slide minoxalune

Minoxidil Typical Outcomes

Clinically-backed results you can trust—supported by real data and patient experiences.

85%

Up to 85% of Men See Hair Regrowth

70%

70% More Hair Growth vs. Control in Men

80%

80% of Women Improved Hair Count after 6 Months

GLP-1
NAD+

Calocurb

Sermorelin

Sinetrol

DNF-10

Epithalon

Diclofenac

Elastira

Finesteride

Minoxidil

Real patients. Real results. Real support—every step of the way.

Hear From Our Clients

“The form process was very simple to follow and submit. The Doctor review was thorough and handled very quickly. Medication is sent next day and I’m well on my way to my wait loss goal. Six weeks on the program and I’m down 30 pounds.”
Kelly P
Kelly P
“I ordered my meds from directmeds.com and I LOVE LOVE LOVE Direct Meds!! It’s has seriously been the biggest blessing!!! They were totally upfront with the monthly cost with NO surprise or hidden fees. I was connected to my doctor and approved within the first day, and my medication arrived 2 days later. When I finished the program I ended up losing 50 pounds!!!! I was at 176 Ibs down and now I’m 126 lbs. This has totally changed my life!!!!”
Sarah H
Sarah H
“I was having technical difficulty, grace called me back and stayed on the phone with me whole time, she was amazing, knowledgable and patient thank you.”
Donna H
Donna H
“Perfection with GRACE. After desperately trying to navigate your website, I had the pleasure to talk with an angel named Grace Herr. Not only was she informative and helpful but went above and beyond to make sure everything was perfect and pleasant. Everyone needs a little grace, I sure did. Well done.”
Robyn R
Robyn R
“Over the moon with Direct Meds for getting my medication to me super fast! I received my medication fast after filling out the paperwork. When I have had a question I get a response within 24 hours. The doctor has been available for questions. I have been on my weight loss medication for 4 weeks and I am down 13 pounds. I eat a lot less and I don’t have food on my brain 24/7. I am so happy 😀”
Teresa P
Teresa P
“My experience with Direct Meds was awesome! The process to apply was very straight forward and fast. It shipped directly to me which was very convenient and it even comes wrapped up in an ice pack to preserve the medication which was cool. Instructions on how to inject the GLP-1 medications were very detailed and made me a lot more comfortable doing it. It was virtually painless and the very next day I already noticed a change in my appetite. I’ve been on it for a week now and it has made a difference! I also love how I can communicate directly with the prescribing doctor with any questions or concerns.”
Canyon H
Canyon H

Frequently Asked questions

Get answers to your questions and find the right solutions for your journey.

Christian from Wisconsin

Charles from New York asks,

What are the most effective treatments for weight loss?

DirectMeds

Direct Meds Team

The most effective treatments available today are GLP-1 receptor agonists like Semaglutide and Tirzepatide. These medications are clinically proven to help patients lose between 15–21% of their body weight by curbing appetite, reducing food noise, and improving metabolic function. At Direct Meds, we prescribe compounded versions of these medications through licensed providers. Our patients can choose between once-weekly injections or sublingual drops, all supported by real nursing staff and shipped directly to their door. It’s fast, safe, and highly effective.

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Angela from Tampa asks,

How quickly will I start seeing results?

DirectMeds

Direct Meds Team

Every body is different, but most of our patients report reduced cravings and more control over food within the first 2–4 weeks. Visible weight loss often begins by week 6, with major progress seen over the first 3 to 6 months. Our licensed nurses check in throughout your journey to optimize dosing and support consistency. Because our GLP-1 medications are clinically backed, the results are sustainable—not just fast, but lasting.

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Carlos from Austin asks,

What’s the difference between Semaglutide and Tirzepatide?

DirectMeds

Direct Meds Team

Great question. Both medications are powerful GLP-1 treatments, but Tirzepatide also activates a second hormone receptor called GIP, which may result in even greater weight loss for some people. On average, Tirzepatide patients lose around 21% of their body weight, compared to 15–16% with Semaglutide. That said, individual experiences vary. Our team helps you decide which medication is best based on your body, goals, and preferences—including the choice between injections or sublingual delivery.

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Melissa from Chicago asks,

Do I need to go to a doctor’s office to get started?

DirectMeds

Direct Meds Team

Nope—no appointments needed. Everything is handled through a secure online quiz and virtual intake form that you can complete in minutes, from anywhere. Once submitted, a licensed medical provider reviews your case within just a few business hours. If you're approved, your personalized prescription is prepared and shipped directly to your door within 1 business day—no pharmacy lines or delays. Every patient also receives ongoing access to our nursing staff for questions, support, and follow-ups throughout the journey. It’s real medical care, made simple, and designed to fit your life—not the other way around.

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Kevin from San Diego asks,

Are there any side effects with GLP-1 medications?

DirectMeds

Direct Meds Team

Like any medication, GLP-1s can cause side effects, but most are mild and temporary. The most common include nausea, constipation, fatigue, or slight appetite changes in the first couple of weeks. These symptoms often subside as your body adjusts. That’s why we include nurse access with every plan—you’re never left guessing. If you ever feel unsure or need a dose adjustment, our team is here for you.

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Sophie from Atlanta asks,

What’s the difference between injections and sublingual drops?

DirectMeds

Direct Meds Team

Our patients love having options. The injectable form is taken once a week with a small, painless shot—very easy and quick. The sublingual drops are taken under the tongue every 1–2 days and are perfect for those who prefer a needle-free option. Both forms use the same active ingredients and have similar outcomes. It really comes down to what fits your lifestyle better—and we help guide that choice during the intake process.

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Tyler from Denver asks,

Is Direct Meds legit?

DirectMeds

Direct Meds Team

Yes—we are a fully LegitScript-certified, HIPAA-compliant telehealth provider with more than 53,000 satisfied patients and an average 4.8-star rating. We work exclusively with licensed providers and FDA certified pharmacies, and all prescriptions are reviewed by a real provider before being shipped. Our medications undergo third-party testing for purity, safety, and potency, and our entire patient experience is designed to be transparent, supportive, and results-driven. You won’t find hidden fees, questionable sourcing, or automated bots here—just high-quality care from real humans who care.

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Olivia from Nashville asks,

How much does this cost, and are there hidden fees?

DirectMeds

Direct Meds Team

No hidden fees—ever. Our pricing is all-inclusive, meaning everything from the medication itself to nurse support, shipping, and digital follow-ups is bundled into one clear monthly rate. Plans start at $249/month for sublingual Semaglutide, and $297/month for injections. We also offer new customer discounts, bulk pricing for 6- or 12-month plans, and accept HSA/FSA payments. What you see is what you pay—no subscriptions, no surprise charges, and no pressure.

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Ben from Phoenix asks,

Can I pay with HSA or FSA funds?

DirectMeds

Direct Meds Team

Absolutely. Direct Meds accepts HSA (Health Savings Account) and FSA (Flexible Spending Account) payments for all GLP-1 treatments. It’s a convenient way to use pre-tax dollars for medically necessary care. Once approved, we can provide receipts and documentation for reimbursement, if needed. This helps many of our patients make their care more affordable while staying compliant with insurance or employer guidelines.

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Lena from Seattle asks,

What happens after I sign up?

DirectMeds

Direct Meds Team

Once you complete the intake quiz, your responses are securely reviewed by one of our licensed medical providers. If you qualify, your prescription is compounded at a certified U.S. pharmacy and shipped within 1 business day. You’ll receive tracking details by email or SMS, and from there, your journey begins. What makes Direct Meds different is the ongoing support—you’ll receive check-ins, nurse access, and a dedicated care team that helps track your progress, optimize your treatment, and make sure your experience is as effective and seamless as possible.

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Heather from Scottsdale asks,

What if I’ve tried everything else and nothing’s worked?

DirectMeds

Direct Meds Team

You’re not alone—many of our patients come to us after years of trying every diet, workout plan, and supplement with little to no success. The truth is, weight loss isn’t just about willpower—it’s biology. That’s where GLP-1 medications like Semaglutide and Tirzepatide can help. These treatments regulate appetite, slow digestion, and improve metabolic function, making it easier to lose weight and keep it off. If you’re feeling stuck, we offer a proven, medically supervised path forward—with personalized care, fast delivery, and real human support. This might finally be the solution that works for you.

Ready to Start?

Start your journey towards a healthier you!
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