Starting at $147 - Doctor-prescribed
GLP-1 treatment delivered to your door.
No insurance needed.
we've been featured all over






Average reduction in
body weight
Average reduction in
waist size
Users say this is more effective than anything they've ever tried
Users have achieved lasting weight loss
Adjust the slider to see what's possible
by the end of fall.
Ready to lose 15% of your body weight?
Get Your Weight Loss
Meds In 1-2 Days
Answer a short quiz about your goals, health history, and what you've already tried. Takes 2 minutes.
A licensed clinician reviews your information and writes a personalized prescription - no office visit needed.
Your Prescription
Semaglutide | 1.5mg/ml
Your medication is cold-packed and delivered to your door in 1-2 days with clear instructions & ongoing support.
Feel full sooner and stay satisfied longer, so you naturally eat less without constantly thinking about food.
Reduce food noise and impulsive eating, making it easier to stick to your plan without relying on willpower.
Lose weight consistently over time with a plan designed to support long-term, sustainable results.
Feel lighter, more energized, and mentally sharper as your body adapts and your habits improve.
Choose Your Medication
That Fits Your Lifestyle
Select the GLP-1 treatment that best matches your weight-loss goals, with medical guidance and fast delivery to your door.
What's Included With
Your GLP-1 Program
Starting
From
Why Patients Choose Direct Meds
Patients choose Direct Meds for a clearer, more straightforward approach to medical weight loss - combining trusted clinical oversight with simple, predictable pricing.
















One simple price with everything included. No insurance required.
The same price across all doses. No memberships or hidden fees.
100% online process. Medications delivered in as little as 2-3 business days.
USA licensed physicians working directly with licensed USA compounding pharmacies.
The Direct Meds Difference
Real, doctor-prescribed GLP-1 medication — not risky
research peptides that were never made for human use.
Research
Peptides
Direct Meds Guarantee
The only thing you'll lose is
the extra weight
We're so confident in our personalized program, we guarantee you'll lose weight or your money back. It's that simple.
250,000+
Happy Customers :)
Real results, real people. Discover how we've transformed lives.
Absolutely incredible!
I take it once a week and I cannot believe how fast I am losing weight. I just don't eat like I used to. I naturally just crave healthier stuff. I'm down to 220 from 245 and I've been on it for only 3 months.
B.H.
Verified BuyerA miracle
A miracle, has changed my life mentally and physically. Also, no desire to drink, a side benefit? I didn't do anything, this is all science. I pray it continues to work. Great delivery system.
Johnny J.
Verified BuyerOne week since my first injection, I lost 6 lbs
Today, in one week since my first injection, I lost 6 lbs. In one week, the last diet (one of very many), it took me 3 months to lose 10 lbs by starving myself.
Mary
Verified BuyerHighly Recommend
The process was seamless and the results were faster than I expected. 5 stars!
Naomi R.
Verified BuyerFrequently Asked Questions

Jessica from Texas,
How does Direct Meds work?
Direct Meds allows you to get prescription weight loss medications such as semaglutide & tirzepatide from the comfort of your home. Your pricing is one simple monthly price and includes medication, supplies, doctor review and shipping. Once you've selected and paid for the first month of your chosen medication, you will need to complete an intake form for the doctor to review and approve your prescription. Once your doctor approves your prescription, our pharmacies will ship out your medication within 2 business days.
When you run out of your medication, you simply let your doctor know in your Direct Meds Patient Portal and your Doctor will review your dosage, adjust it if needed, and write you a new prescription that gets delivered next day via UPS or FedEx.
*If for any reason your prescription is not approved, you will receive a full refund.

Sarah from Florida asks,
How do I know this is safe?
Direct Meds has taken numerous steps to ensure compliance and safety for our patients.

Diana from Ohio asks,
So how does the signup process work?
*If for any reason your prescription is not approved, you will receive a full refund.

Eric from Virginia asks,
What States/Juristictions are eligible?
Direct Meds currently provides services to all US States EXCEPT Mississippi and Louisiana where prescription of weight loss medications via telehealth is prohibited.

Jasmine from Arizona asks,
How does the pricing work?
Direct Meds partners with licensed doctors and pharmacy to offer competitive pricing on compounded GLP-1 weight loss medications. Our pricing is transparent with no hidden costs or monthly fees.
For Semaglutide we charge $297/month. For Tirzepatide we charge $399/month.
Included in this simple pricing is your medication, doctors visits (normally $99/visit), 1-day FedEx or UPS shipping, and all supplies needed for injections.
Competitors will often charge ‘access’ or membership fees. Direct Meds does not have those so that pricing is extremely clear and you don’t get surprise costs.

Ashley from Georgia asks,
What if I need to cancel?
With Direct Meds there are no contracts for our month to month pricing. We also offer subscribe and save discounts where customers will agree to a subscription length for stated monthly discount. Month to month customers can cancel their shipment anytime by sending an email to [email protected] or call us at 888-696-7176. We want to make sure that our customers love the results of our treatment plans so we offer a patient satisfaction guarantee. If you are unhappy with your results, let us know and we’ll make it right.

Sarah from Florida asks,
Is the medication real semaglutide & tirzepatide?
Yes, both of our GLP-1 weight loss medications are real prescription medications that are prescribed by a doctor and compounded by a real US based pharmacy. We offer only the best Semaglutide and Tirzepatide medications for weightloss management for customers that meet the qualifications required for GLP-1 medications. These are the same medications that people are talking about and getting real results with all over social media.
Direct Meds Semaglutide Purity Analysis
Direct Meds Tirzepatide Purity Analysis

David from Nebraska,
Do you offer non-injectable options?
Yes! We currently offer oral sublingual Semaglutide and Tirzepatide. Studies show this medication is a great and effective alternative to injections.

Karen from Oregon asks,
What is the dosage I’ll be taking?
Our medical practitioner will ultimately decide what is right for you. However, our standard protocol for many patients is:
Medication 1:
0.25mg/week for the first 4 weeks
0.5 mg/week for the next 8 weeks
Dosage will include Ondanestron (brand name Zofran®)
Medication 2:
10/mg for the first 4 weeks
20/mg for the next 8 weeks

Danielle from Minnesota asks,
Where do my prescriptions come from?
Medications prescribed through Direct Meds are dispensed by U.S.-based 503A compounding pharmacies. These pharmacies prepare medications individually in response to a prescription from a licensed healthcare provider and must follow applicable federal and state compounding regulations, as well as professional standards such as USP 795 and USP 797.
Compounded medications are prepared for individual patients when commercially available alternatives are not suitable. They are not FDA-approved, but 503A compounding pharmacies are licensed by state pharmacy boards and operate under federal compounding laws.
Alert
Direct Meds is not able to provide services in Mississippi or Louisiana, where state regulations currently restrict the prescribing of weight-management medications via telehealth.

Michelle from Texas asks,
How do I take my medication?
For Semaglutide & Tirzepatide Injections:
You will be provided with small insulin sized needles along with your medication. Your doctor will explain how and when to take your medication during your telemed visit. You will start with a low dose to begin your treatment once per week as your body gets used to the medication and increase your dose every 4 weeks until you are at your full dosage. Medication will be administered by injecting into the fatty area on your stomach weekly.
For our non-injectable Semaglutide option, it’s important to follow the correct steps to ensure proper absorption and effectiveness:
For Compounded Semaglutide & Tirzepatide Sublingual Drops:
Use the dropper to place the prescribed amount (typically 0.5 mg) under your tongue. Hold the drops under your tongue for 1-2 minutes before swallowing to ensure proper absorption. Take the drops daily for 4 weeks as directed, with higher dosing options available if recommended by your healthcare provider. Avoid eating, drinking, or smoking for at least 15 minutes before and after taking the drops.
Following these instructions will help you get the most out of your Semaglutide treatment. If you have any questions, feel free to contact our support team for guidance!

Christina from North Carolina asks,
How is it shipped?
Prescriptions received before 2 pm central time will be shipped the same day. Your prescription will be shipped next-day via UPS in a temperature controlled package. To ensure temperature management and weekend orders (Friday-Sunday) will be shipped Monday. You’ll receive a tracking number for every shipment. Each shipment is fully insured for lost prescriptions. The only exception for insured product replacement is if a patient provides incorrect shipping information. If this occurs, please speak with customer service by emailing [email protected] or calling us at (888) 696-7176.

Megan from Nevada asks,
How much weight will I lose?
Individual weight-loss is dependent on a number of factors but on average patients using these weight loss medications report an average loss of 1.5% of their body weight per week. Over 12 weeks, it can be as high as 10%. This equates to a weight loss of 10–20 pounds for a 200 pound person.

Heather from Linda,
How do I contact support?
You can reach our friendly support team by emailing [email protected] or calling us at (888) 696-7176. For faster service, visit our Patient Services page to submit a message, request a refill, or check order status. We're here to help!
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It's not cheating, it's science! Lose up to 15% of your body weight (1-2 lbs per week) with medically supervised, safe & effective treatment from the comfort of your home.